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What is metabolic disease


1. What is metabolic disease.

Metabolic disorders are manifestations of systemic disorders in the brain. Due to the occurrence of the blood-brain barrier, the brain tissue is affected by the biochemical environment and undergoes metabolic changes, resulting in brain dysfunction. Common causes are diabetes, uremia, hypercalcemia, and liver failure. Brain dysfunction is often obvious, but pathological changes are not obvious. The nature of this encephalopathy is primarily a biochemical disorder.

2. Metabolic disorders of metabolic diseases.

Congenital metabolic disorders often result in multisystem effects. Clinically, some are neurological, some are extra-neurological, such as patients with hepatolenticular degeneration, some are mainly manifested as liver dysfunction and mild neurological symptoms; other patients have prominent neurological symptoms, manifested as chorea symptoms, hands and feet. Slow motion or dementia. Another example is a patient with phenylketonuria, a metabolic disorder that spreads throughout the body, but the clinical symptoms of the nervous system are particularly pronounced.

3. Pathogenesis of metabolic diseases.

Primary nutritional disorders result in insufficient nutrient intake. Excessive or improperly proportioned. For example, insufficient protein intake leads to protein deficiency, and excessive energy intake leads to obesity. Secondary nutritional disorders are caused by organic or functional diseases. Genetic mutations in inherited metabolic disease examples (inborn errors of metabolism) lead to structural and functional impairment of proteins and the disappearance of reactions catalyzed by specific enzymes. Decreases or (incidentally) increases lead to abnormal cell and organ function.

Causes of metabolic disease.

1. Lack of protein. In order to reduce the cost of self-prepared feed, local farmers cannot obtain high-quality feed. Protein, or replacing it with a large amount of vegetable protein and grain feed, causes fur animals to grow slowly due to insufficient protein. The quality of the plush is reduced. The skin level is reduced or the skin is too thin, the male animal is not in heat or the quality of the semen is reduced. The female beast is not in good heat. No ovulation, even miscarriage and embryo absorption. Solution: By enriching the source of animal feed and combining various raw materials with high-protein digestible feed, the purpose of increasing protein content and reducing feed cost is achieved.

2. Lack of fat. Insufficient fat content in the feed can lead to malabsorption of fat-soluble vitamins and induce corresponding vitamin deficiencies. Lack of fat content can also lead to poor skin gloss, disheveled hair, and reduced skin levels. Fat is also an important nutrient that is easy to absorb, providing a lot of energy needed by the body. If it is lacking, it can also be induced. Insufficient intake can lead to growth retardation. Too high fat content can lead to diseases such as indigestion and diarrhea. Fat content should be strictly controlled to prevent the occurrence of yellow fat disease. The amount of grain feed is too large. Local farmers have the problem of excessive use of grain feed.

Hazards of congenital metabolic diseases.

1. Congenital metabolic diseases are mainly due to genetic mutations related to genetics, leading to defects in certain enzymes or structural proteins, resulting in disorders of amino acid or organic acid metabolism in the body, producing abnormal metabolites, and accumulating in the body of newborns. Excreted through sweat and urine, giving off all kinds of strange odors. Diabetes, for example, can smell like caramel. Curry smell; phenylketonuria, which smells of consumables; methionine malabsorption, which smells like a hop oven; hypermethioninemia, which smells like boiled cabbage or stale butter; butyric acidemia, which smells like stinky fish And the smell of shrimp; pyroglutamate can give off the smell of sweaty feet.

2. Neonatal sepsis is a common serious bacterial infectious disease in newborns. It is caused by bacteria invading the blood circulation, growing, multiplying and producing toxins in the blood. The disease has high morbidity and mortality, and can be cured with aggressive anti-infective treatment as soon as possible. After being ill, children may present with aggravated primary jaundice, unstable body temperature, and fever in most cases, but sometimes the body temperature is normal or not raised. Preterm infants may appear grey. Weak all over. Inability to suck. Low cry, low response.